The purpose of containment is to prevent reintroduction of wild polioviruses from laboratories into polio-free communities.In order to achieve global commitment to laboratory containment the rationale should be clear and compelling; the biosafety levels should be justified by the risks; and the objectives should be realistic.Absolute containment ca
Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells.
STAT3 activation is frequently detected in breast cancer and this pathway has emerged as Show Halters an attractive molecular target for cancer treatment.Recent experimental evidence suggests ALDH-positive (ALDH(+)), or cell surface molecule CD44-positive (CD44(+)) but CD24-negative (CD24(-)) breast cancer cells have cancer stem cell properties.How
Rheological and mechanical consequences of reducing the curing time of cold asphalt mixtures by means of magnetic induction
Cold asphalt mixtures are more sustainable because they are manufactured at ambient temperature.However, they are much less applied because they take longer time in the curing process due to the water contained in the asphalt emulsion, which delays the opening Bikini top of roads.To solve this problem, the option of adding magnetic aggregates to co
Mobile homes in the land of illness: the hospitality and hostility of language in doctor-patient relations
Abstract Illness has a way of disorientating us, as if we are cast adrift in a foreign land.Like strangers in a dessert we seek oasis to recollect ourselves, find refuge and learn to build our own shelters.Using the philosophy of Levinas and Derrida, we can interpret health care providers (HCP), and the sites from which they act (e.g.hospitals), as
Image microarrays derived from tissue microarrays (IMA-TMA): New resource for computer-aided diagnostic algorithm development
Background: Conventional tissue microarrays (TMAs) consist of cores of tissue inserted into a recipient paraffin block such that a tissue section on a single glass slide can contain numerous patient samples in a spatially structured pattern.Scanning TMAs into digital slides for subsequent analysis by computer-aided diagnostic (CAD) algorithms all o